| Description | Lidoflazine is a high-affinity blocker of the HERG K+ channel and is an antianginal calcium channel blocker. It carries an obvious risk of QT interval prolongation and ventricular arrhythmia. |
| In vitro | Lidoflazine inhibits effectively HERG current (IHERG). This recorded from HEK 293 cells stably expressing wild-type HERG (IC50: ~16 nM). |
| molecular weight | 491.62 |
| Molecular formula | C30H35F2N3O |
| CAS | 3416-26-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. https://www.ncbi.nlm.nih.gov/pubmed/15135665 |