| Description | LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); exhibits no inhibitory activity at CK2. |
| Target activity | CK1ε:1.3 μM, CK1α:2.5 μM, CK1δ:290 nM |
| Synonyms | LH-846, LH 846 |
| molecular weight | 316.81 |
| Molecular formula | C16H13ClN2OS |
| CAS | 639052-78-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (173.61 mM) |
| References | 1. Lee JW, et al. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11. |