| Description | Levovirin (L-Ribavirin), the L-enantiomer of ribavirin, is a guanosine nucleoside analog with immunomodulatory activity and is used in the study of hepatitis C virus infection. |
| Synonyms | ICN-17261, ICN 17261, ICN17261, L-Ribavirin |
| molecular weight | 244.20 |
| Molecular formula | C8H12N4O5 |
| CAS | 206269-27-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Fang C, et al. Effect of ribavirin, levovirin and viramidine on liver toxicological gene expression in rats. J Appl Toxicol. 2003 Nov-Dec;23(6):453-9. 2. Lin CC,et al. Absorption, pharmacokinetics and excretion of levovirin in rats, dogs and cynomolgus monkeys. J Antimicrob Chemother. 2003 Jan;51(1):93-9. 3. Li F, et al. Transport of levovirin prodrugs in the human intestinal Caco-2 cell line. J Pharm Sci. 2006 Jun;95(6):1318-25. 4. Lin CC, et al. Specific, sensitive and accurate LC-MS/MS method for the measurement of levovirin in rat and monkey plasma. J Pharm Biomed Anal. 2002 Sep 5;30(2):239-46. |