| Description | Levallorphan tartrate is an opioid antagonist with properties similar to those of NALOXONE. Levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants. |
| Synonyms | Lorfan |
| molecular weight | 433.49 |
| Molecular formula | C23H31NO7 |
| CAS | 71-82-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. MILLER JW, GILFOIL TM, SHIDEMAN FE. The effects of levallorphan tartrate (levo-3-hydroxy-N-allylmorphinan tartrate) on the respiration of rabbits given morphine. J Pharmacol Exp Ther. 1955 Nov;115(3):350-9. PubMed PMID: 13272187. 2. GRUBER CM Jr. Effect of levallorphan tartrate upon toxicity of morphine. Proc Soc Exp Biol Med. 1955 Feb;88(2):189-91. PubMed PMID: 14357383. 3. RANKIN J, MEHNERT J, CURRERI AR. Effect of levallorphan tartrate on levorphanol tartrate analgesia in postoperative patients. AMA Arch Surg. 1957 Apr;74(4):602-5. PubMed PMID: 13410340. 4. SCHNIEDEN H. The effect of levallorphan tartrate and of adiphenine hydrochloride on the antidiuretic action of morphine and nicotine. Br J Pharmacol Chemother. 1960 Dec;15:510-2. PubMed PMID: 13748312; PubMed Central PMCID: PMC1482260. |