| Description | Leustroducsin B is a novel colony-stimulating factor (CSF) inducer extracted from Streptomyces platensis SANK 60191. |
| Synonyms | LSN B |
| molecular weight | 669.78 |
| Molecular formula | C34H56NO10P |
| CAS | 145142-82-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Trost BM, Biannic B, Brindle CS, O'Keefe BM, Hunter TJ, Ngai MY. A Highly Convergent Total Synthesis of Leustroducsin B. J Am Chem Soc. 2015 Sep 16;137(36):11594-7. doi: 10.1021/jacs.5b07438. Epub 2015 Sep 1. PubMed PMID: 26313159; PubMed Central PMCID: PMC4621997. 2. Greszler SN, Malinowski JT, Johnson JS. Formal synthesis of leustroducsin B via Reformatsky/Claisen condensation of silyl glyoxylates. Org Lett. 2011 Jun 17;13(12):3206-9. doi: 10.1021/ol2011192. Epub 2011 May 17. PubMed PMID: 21591684; PubMed Central PMCID: PMC3115596. 3. Miyashita K, Tsunemi T, Hosokawa T, Ikejiri M, Imanishi T. Total synthesis of leustroducsin B. J Org Chem. 2008 Jul 18;73(14):5360-70. doi: 10.1021/jo8005599. Epub 2008 Jun 13. PubMed PMID: 18549287. 4. Koishi R, Yoshimura C, Kohama T, Serizawa N. Leustroducsin B activates nuclear factor-kappaB via the acidic sphingomyelinase pathway in human bone marrow-derived stromal cell line KM-102. J Interferon Cytokine Res. 2002 Mar;22(3):343-50. PubMed PMID: 12034042. |