| Description | LEP(116-130)(mouse) is a synthetic leptin peptide fragment. |
| In vivo | 与对照组的小鼠相比，LEP-(116-130)（1 mg, i.p.）在食物摄入量增加的情况下，能显著降低体重增长速率。同时，LEP-(116-130)大约降低了100 mg/dL的血糖水平。 |
| Target activity | C5aR:20 nM |
| molecular weight | 1674.77 |
| Molecular formula | C66H110F3N19O26S |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 50 mg/mL (32.04 mM), Sonication is recommended. |
| References | 1. Grasso P, et al. Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor. Diabetes. 1999 Nov;48(11):2204-9. |