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Lenalidomide-C5-amido-Boc

CAS No.: 2138441-25-3

Lenalidomide-C5-amido-Boc is a Cereblon ligand derived from Lenalidomide, and serves in the recruitment of CRBN protein.
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Description Lenalidomide-C5-amido-Boc is a Cereblon ligand derived from Lenalidomide, and serves in the recruitment of CRBN protein. It can be effectively linked to the protein ligand through a linker, resulting in the formation of PROTAC.
Synonyms Lenalidomide-C5-amido-Boc
molecular weight 429.517
Molecular formula C23H31N3O5
CAS 2138441-25-3
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Wang, Shaomeng, et al. Preparation of phthalimide-based compounds as monofunctional intermediates for ligand-dependent target protein degradation. World Intellectual Property Organization, WO2017176958 A1 2017-10-12. 2. Robbins, Daniel, et al. WBifunctional compounds for degrading BTK via ubiquitin proteasome pathway. World Intellectual Property Organization, WO2021091575 A1 2021-05-14.