PeptideDB

LEM-14

CAS No.: 1814881-70-3

LEM-14 is a potent NSD2-specific inhibitor (IC50:132 μM).LEM-14 may be used in the study of multiple myeloma.
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Description LEM-14 is a potent NSD2-specific inhibitor (IC50:132 μM).LEM-14 may be used in the study of multiple myeloma.
Target activity NSD2:132 µM
molecular weight 478.56
Molecular formula C25H26N4O4S
CAS 1814881-70-3
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 45.0 mg/mL (94.0 mM ), Sonication is recommended.
References 1. Shen Y, et al. Identification of LEM-14 inhibitor of the oncoprotein NSD2. Biochem Biophys Res Commun. 2019 ; 508(1):102-108.