| Description | Ledipasvir (acetone) (GS-5885 acetone) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection. |
| Target activity | GT1a:34 pM (EC50), GT1b:4 pM(EC50) |
| Synonyms | Ledipasvir acetone, 雷迪帕韦单丙酮溶剂化物, GS-5885 acetone, 雷迪帕韦单丙酮 |
| molecular weight | 947.08 |
| Molecular formula | C52H60F2N8O7 |
| CAS | 1441674-54-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Ethanol: 100 mg/mL (112.48 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 100 mg/mL (112.48 mM) |
| References | 1. Smith MA, et al. Ann Pharmacother. 2015 Mar;49(3):343-50. |