| Description | Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated β-amyloid (Abeta) with activity against oligomers, protofibrils, and insoluble protofibrils, and may be useful in the study of Alzheimer's disease (AD)-induced mild cognitive impairment and mild AD dementia. |
| Synonyms | BAN-2401 |
| molecular weight | N/A |
| CAS | 1260393-98-3 |
| Storage | store at low temperature | store at -20°C |
| References | 1. Van Dyck CH,et al. Lecanemab in Early Alzheimer's Disease. N Engl J Med. 2023 Jan 5;388(1):9-21. 2. Vitek GE,et al. Lecanemab (BAN2401): an anti-beta-amyloid monoclonal antibody for the treatment of Alzheimer disease. Expert Opin Investig Drugs. 2023 Feb;32(2):89-94. |