| Description | LDN-211904 oxalate (compound 32), a potent and selective EphB3 inhibitor, demonstrates an IC50 of 0.079 μM and shows good metabolic stability in mouse liver microsomes. When combined with cetuximab, it may effectively inhibit STAT3-activated CSC stemness and cetuximab resistance in CRC [1] [2]. |
| molecular weight | 444.87 |
| Molecular formula | C21H21ClN4O5 |
| CAS | 1198408-78-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |