Description | Lauryl maltose neopentyl glycol is a detergent that solubilizes and stabilizes membrane proteins.Lauryl maltose neopentyl glycol extracts intact membrane proteins from membranes, which improves the stabilization of membrane proteins such as G-protein coupled receptors and respiratory complexes.Lauryl maltose Lauryl maltose neopentyl glycol is solubilizing. |
In vitro | 在不妨碍无细胞反应的洗涤剂浓度下,lauryl maltose neopentyl glycol 有助于溶解性膜蛋白的生产。[2] |
Synonyms | LMNG |
molecular weight | 1005.19 |
Molecular formula | C47H88O22 |
CAS | 1257852-96-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility | Methanol: 112.5 mg/mL (111.9 mM), Sonication is recommended. H2O: 90.0 mg/mL (89.5 mM), Sonication is recommended. DMSO: 90.0 mg/mL (89.5 mM), Sonication is recommended. |
References | 1. Breyton C, et, al. Assemblies of lauryl maltose neopentyl glycol (LMNG) and LMNG-solubilized membrane proteins. Biochim Biophys Acta Biomembr. 2019;1861(5):939-957. 2. Fogeron ML, et, al. Wheat germ cell-free expression: Two detergents with a low critical micelle concentration allow for production of soluble HCV membrane proteins. Protein Expr Purif. 2015;105:39-46. 3. Alonso H, et al. Characterization and two-dimensional crystallization of membrane component AlkB of the medium-chain alkane hydroxylase system from Pseudomonas putida GPo1. Appl Environ Microbiol. 2012;78(22):7946-7953. |