| Description | Lauroyl-coenzyme A can function as an acyl group carrier, acetyl-CoA. It can be used as an intermediate in lipid metabolism and is involved in lipid biosynthesis and fatty acid transport. |
| Synonyms | Dodecanoyl-coa, Coenzyme A, lauroyl-, Lauroyl-coa |
| molecular weight | 949.84 |
| Molecular formula | C33H58N7O17P3S |
| CAS | 6244-92-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Musayev F, Sachdeva S, Scarsdale JN, Reynolds KA, Wright HT. Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A. J Mol Biol. 2005 Mar 11;346(5):1313-21. Epub 2005 Jan 20. PubMed PMID: 15713483. 2. Poosch MS, Yamazaki RK. Determination of peroxisomal fatty acyl-CoA oxidase activity using a lauroyl-CoA-based fluorometric assay. Biochim Biophys Acta. 1986 Dec 10;884(3):585-93. PubMed PMID: 3778940. 3. Oba Y, Sato M, Ojika M, Inouye S. Enzymatic and genetic characterization of firefly luciferase and Drosophila CG6178 as a fatty acyl-CoA synthetase. Biosci Biotechnol Biochem. 2005 Apr;69(4):819-28. PubMed PMID: 15849423. 4. Tamvakopoulos CS, Willi S, Anderson VE, Hale DE. Long-chain acyl-CoA profiles in cultured fibroblasts from patients with defects in fatty acid oxidation. Biochem Mol Med. 1995 Jun;55(1):15-21. PubMed PMID: 7551821. |