Laurocapram Bioactivity,Chemical Properties,Storage & Solubility Information Pathways-PeptideDB

Description	Laurocapram (N-Lauryl caprolactam) is a percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the skin to absorb a hydrophilic chemical.
Synonyms	月桂氮酮, Tranzone, Azone, N-Lauryl caprolactam, N-0252, 月桂氮卓酮, N-Dodecylcaprolactam
molecular weight	281.48
Molecular formula	C18H35NO
CAS	59227-89-3
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility	DMSO: 50 mg/mL (177.63 mM)
References	1. Xue, X., Zhou, Y., Chen, Y., Meng, J., Jia, M., & Hou, Z. et al. (2011). Promoting effects of chemical permeation enhancers on insulin permeation across TR146 cell model of buccal epitheliumin vitro. Drug And Chemical Toxicology, 35(2), 199-207. doi: 10.3109/01480545.2011.589848 2. del Rio-Sancho, S., Serna-Jiménez, C., Calatayud-Pascual, M., Balaguer-Fernández, C., Femenía-Font, A., Merino, V., & López-Castellano, A. (2012). Transdermal absorption of memantine – Effect of chemical enhancers, iontophoresis, and role of enhancer lipophilicity. European Journal Of Pharmaceutics And Biopharmaceutics, 82(1), 164-170. doi: 10.12016/j.ejpb.2012.06.2005

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