| Description | Larsucosterol is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis. |
| Synonyms | DUR-928 |
| molecular weight | 482.72 |
| Molecular formula | C27H46O5S |
| CAS | 884905-07-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Ren S, Hylemon P, Zhang ZP, Rodriguez-Agudo D, Marques D, Li X, Zhou H, Gil G, Pandak WM. Identification of a novel sulfonated oxysterol, 5-cholesten-3beta,25-diol 3-sulfonate, in hepatocyte nuclei and mitochondria. J Lipid Res. 2006 May;47(5):1081-90. doi: 10.1194/jlr.M600019-JLR200. Epub 2006 Feb 27. PMID: 16505492. 2. Wang Y, Li X, Ren S. Cholesterol Metabolites 25-Hydroxycholesterol and 25-Hydroxycholesterol 3-Sulfate Are Potent Paired Regulators: From Discovery to Clinical Usage. Metabolites. 2020 Dec 25;11(1):9. |
| Citations | 1. Wu L, Tian X, Du H, et al. Bioinformatics Analysis of LGR4 in Colon Adenocarcinoma as Potential Diagnostic Biomarker, Therapeutic Target and Promoting Immune Cell Infifiltration. Biomolecules. 2022, 12(8): 1081 |