| Description | LAQ 824 is an inhibitor of histone deacetylase. |
| Synonyms | LAQ824, LAQ-824 |
| molecular weight | 379.46 |
| Molecular formula | C22H25N3O3 |
| CAS | 591207-53-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Rosato RR, Almenara JA, Maggio SC, Coe S, Atadja P, Dent P, Grant S. Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions. Mol Cancer Ther. 2008 Oct;7(10):3285-97. doi: 10.1158/1535-7163.MCT-08-0385. PubMed PMID: 18852132; PubMed Central PMCID: PMC2586957. 2. Ganai SA. Strategy for enhancing the therapeutic efficacy of histone deacetylase inhibitor dacinostat: the novel paradigm to tackle monotonous cancer chemoresistance. Arch Pharm Res. 2015 Oct 19. [Epub ahead of print] PubMed PMID: 26481010. |