PeptideDB

Ladarixin Sodium

CAS No.: 865625-56-5

Ladarixin Sodium, an Chemokine CXCR antagonist, is used potentially for the treatment of type I diabetes.
Sales Email:peptidedb@qq.com

This product is for research use only, not for human use. We do not sell to patients.

Description Ladarixin Sodium, an Chemokine CXCR antagonist, is used potentially for the treatment of type I diabetes.
Synonyms DF 2156A, DF-2156, DF2156A, DF2156, DF 2156, DF-2156A
molecular weight 398.32
Molecular formula C11H12F3NNaO6S2
CAS 865625-56-5
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Citro A, Valle A, Cantarelli E, Mercalli A, Pellegrini S, Liberati D, Daffonchio L, Kastsiuchenka O, Ruffini PA, Battaglia M, Allegretti M, Piemonti L. CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice. Diabetes. 2015 Apr;64(4):1329-40. doi: 10.2337/db14-0443. Epub 2014 Oct 14. PubMed PMID: 25315007. 2. Kemp DM, Pidich A, Larijani M, Jonas R, Lash E, Sato T, Terai M, De Pizzol M, Allegretti M, Igoucheva O, Alexeev V. Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment. Oncotarget. 2017 Jan 24. doi: 10.18632/oncotarget.14803. [Epub ahead of print] PubMed PMID: 28129639. 3. Carreira EU, Carregaro V, Teixeira MM, Moriconi A, Aramini A, Verri WA Jr, Ferreira SH, Cunha FQ, Cunha TM. Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain. Eur J Pain. 2013 May;17(5):654-63. doi: 10.1002/j.1532-2149.2012.00240.x. Epub 2012 Nov 7. PubMed PMID: 23132735.