| Description | L-Tyrosine ((S)-Tyrosine) is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine, considered a non-essential amino acid. L-Tyrosine(L-p-Tyrosine) is the levorotatory isomer of the aromatic amino acid tyrosine. |
| In vitro | L-Tyrosine在体外可抑制后皮层中柠檬酸合成酶的活性。后皮层、海马、纹状体和肝脏中的琥珀酸脱氢酶活性增加。复合体Ⅰ的活性在海马中受到抑制，复合体Ⅱ的活性在海马、后皮层和肝脏中也受到抑制，复合体Ⅱ-Ⅲ的活性不因 L-Tyrosine而改变，复合体Ⅳ的活性在后皮层中降低[1]。 |
| In vivo | 给予L-tyrosine会抑制大鼠后皮质和肝脏中苹果酸脱氢酶和线粒体呼吸链的复合体II、II-III和IV的活性。同时，后皮质中的琥珀酸脱氢酶和复合体I的活性受到抑制，而在纹状体中则有所增加[1]。 |
| Synonyms | Tyrosine, P-Tyrosine, L-酪氨酸, L-p-Tyrosine, (S)-Tyrosine, 酪氨酸 |
| molecular weight | 181.19 |
| Molecular formula | C9H11NO3 |
| CAS | 60-18-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Insoluble H2O: Insoluble |
| References | 1. Ferreira GK, et al. Neurotox Res. 2013, 23(4):327-35. |