Description | L-Homopropargylglycine is a methionine analog commonly used in bioorthogonal non-classical amino acid labeling to detect bacterial activity and to detect protein synthesis. |
In vitro | PROTAC 含有两个不同的配体,它们通过接头连接在一起;一个是 E3 泛素连接酶的配体,另一个是靶蛋白的配体。PROTAC 利用细胞内泛素-蛋白酶体系统选择性地降解靶蛋白[1]。 |
molecular weight | 127.14 |
Molecular formula | C6H9NO2 |
CAS | 98891-36-2 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility | DMSO: 100 mg/mL (786.53 mM), Sonication is recommended. H2O: 60 mg/mL (471.92 mM), Sonication is recommended. |
References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |