| Description | L-asarinin ((-)-Episesamin) reduces peripheral blood concentration of IL-12 and inhibits the expression of CXCR3 and TLR4, which means Asarinin may have a role on the TLR4 pathway and produce prolongation of allograft heart survival. |
| Synonyms | 細辛素, (-)-Episesamin |
| molecular weight | 354.35 |
| Molecular formula | C20H18O6 |
| CAS | 133-05-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/mL (169.32 mM) Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble |
| References | 1. Gu J., et al. The effect of Asarinin on Toll-like pathway in rats after cardiac allograft implantation. Transplant Proc. 2015 Mar;47(2):545-8. 2. Bogurcu N., et al. ALCAPs induce mitochondrial apoptosis and activate DNA damage response by generating ROS and inhibiting topoisomerase I enzyme activity in K562 leukemia cell line. Biochem Biophys Res Commun. 2011 Jun 17;409(4):738-44. |