| Description | L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1]. |
| Synonyms | CTP354, CTP354 (C-21191), C-21191 |
| molecular weight | 408.45 |
| Molecular formula | C19H10D9F2N7O |
| CAS | 1213669-91-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 12 mg/ml (29.38 mM) |
| References | 1. Hofmann M, et al. Assessment of the effects of NS11394 and L-838417, α2/3 subunit-selective GABA(A) [corrected] receptor-positive allosteric modulators, in tests for pain, anxiety, memory and motor function [published correction appears in Behav Pharmacol. 2013 Apr;24(2):153]. Behav Pharmacol. 2012;23(8):790-801. |