| Description | L 738372 is a non-nucleoside inhibitor of HIV-1 reverse transcriptase. |
| Synonyms | L-738,372, L 738,372, L738372, L738,372, L-738372 |
| molecular weight | 289.33 |
| Molecular formula | C18H15N3O |
| CAS | 159565-60-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Wang T, Grinberg N, Bicker G, Tway P, Thompson K. High-performance liquid chromatographic separation of an HIV-1 reverse transcriptase inhibitor and its enantiomer. J Chromatogr A. 1996 Jul 12;738(2):290-4. PubMed PMID: 8696508. 2. Prueksaritanont T, Balani SK, Dwyer LM, Ellis JD, Kauffman LR, Varga SL, Pitzenberger SM, Theoharides AD. Species differences in the metabolism of a potent HIV-1 reverse transcriptase inhibitor L-738,372. In vivo and in vitro studies in rats, dogs, monkeys, and human. Drug Metab Dispos. 1995 Jul;23(7):688-95. PubMed PMID: 7587955. 3. Carroll SS, Stahlhut M, Geib J, Olsen DB. Inhibition of HIV-1 reverse transcriptase by a quinazolinone and comparison with inhibition by pyridinones. Differences in the rates of inhibitor binding and in synergistic inhibition with nucleoside analogs. J Biol Chem. 1994 Dec 23;269(51):32351-7. PubMed PMID: 7528214. |