| Description | L 683519 is one of the Tacrolimus impurities with immunosuppressant and could restrain the activity of FK-506 binding protein. |
| Synonyms | L683519, 13-Desmethyl FK 506, L-683519 |
| molecular weight | 790.004 |
| Molecular formula | C43H67NO12 |
| CAS | 132172-14-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Chen TS, Arison BH, Wicker LS, Inamine ES. Microbial transformation of immunosuppressive compounds. II. Specific desmethylation of 13-methoxy group of FK 506 and FR 900520 by an unidentified Actinomycete ATCC 53828 [corrected]. J Antibiot (Tokyo). 1992 Apr;45(4):577-80. Erratum in: J Antibiot (Tokyo) 1992 Jun;45(6):C-2. PubMed PMID: 1375593. |