| Description | L 657925 is an antagonist of the thromboxane A2 receptor. |
| Synonyms | L-657925, L657925 |
| molecular weight | 373.85 |
| Molecular formula | C21H21ClFNO2 |
| CAS | 122757-59-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Paul RV, Saxenhofer H, Wackym PS, Halushka PV. Stimulation of rat mesangial cell thromboxane A2 receptors inhibits particulate but not soluble guanylyl cyclase. Am J Physiol. 1996 Jan;270(1 Pt 2):F31-8. PubMed PMID: 8769820. 2. Zucker TP, Higashiura K, Mathur RS, Halushka PV. Androstenedione increases thromboxane A2 receptors in human erythroleukemia cells. Life Sci. 1996;58(8):683-90. PubMed PMID: 8594318. 3. Simmons TR, Cook JA, Moore JN, Halushka PV. Thromboxane A2 receptors in equine monocytes: identification of a new subclass of TXA2 receptors. J Leukoc Biol. 1993 Feb;53(2):173-8. PubMed PMID: 8383167. 4. Ueda N, Mayeux PR, Walker PD, Shah SV. Receptor-mediated increase in cytosolic calcium in LLC-PK1 cells by platelet activating factor and thromboxane A2. Kidney Int. 1991 Dec;40(6):1075-81. PubMed PMID: 1662319. |