| Description | L 653328 is an ocular hypotensive agent that has modest beta-receptor blocking activity. |
| Synonyms | L 653,328, L653328, L653,328, L-653,328, L-653328 |
| molecular weight | 309.4 |
| Molecular formula | C17H27NO4 |
| CAS | 115609-61-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Bauer KG, Brunner-Ferber F, Distlerath LM, Lippa EA, Binkowitz B, Till P, Kaik GA. Assessment of bronchial effects following topical administration of butylamino-phenoxy-propanol-acetate, an oculoselective beta-adrenoceptor blocker in asthmatic subjects. Br J Clin Pharmacol. 1992 Aug;34(2):122-9. PubMed PMID: 1358158; PubMed Central PMCID: PMC1381528. 2. Gerin G, Durand-Cavagna G, Gordon LR, Duprat P, Hollander CF. Drug-induced changes in dogs after long term application of a beta-blocker. Lens Eye Toxic Res. 1989;6(1-2):319-29. PubMed PMID: 2577307. 3. Sugrue MF, Gautheron P, Grove J, Mallorga P, Viader MP, Baldwin JJ, Ponticello GS, Varga SL. L-653,328: an ocular hypotensive agent with modest beta receptor blocking activity. Invest Ophthalmol Vis Sci. 1988 May;29(5):776-84. PubMed PMID: 2896641. |