| Description | L-573655, an antibacterial agents, targets lipid A biosynthesis in gram-negative bacteria. |
| Synonyms | L573,655, L 573,655, L 573655, L-573,655 |
| molecular weight | 206.2 |
| Molecular formula | C10H10N2O3 |
| CAS | 112507-21-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Jackman JE, Fierke CA, Tumey LN, Pirrung M, Uchiyama T, Tahir SH, Hindsgaul O, Raetz CR. Antibacterial agents that target lipid A biosynthesis in gram-negative bacteria. Inhibition of diverse UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases by substrate analogs containing zinc binding motifs. J Biol Chem. 2000 Apr 14;275(15):11002-9. PubMed PMID: 10753902. 2. Chen MH, Steiner MG, de Laszlo SE, Patchett AA, Anderson MS, Hyland SA, Onishi HR, Silver LL, Raetz CR. Carbohydroxamido-oxazolidines: antibacterial agents that target lipid A biosynthesis. Bioorg Med Chem Lett. 1999 Feb 8;9(3):313-8. PubMed PMID: 10091675. 3. Onishi HR, Pelak BA, Gerckens LS, Silver LL, Kahan FM, Chen MH, Patchett AA, Galloway SM, Hyland SA, Anderson MS, Raetz CR. Antibacterial agents that inhibit lipid A biosynthesis. Science. 1996 Nov 8;274(5289):980-2. PubMed PMID: 8875939. |