| Description | L-5-BromoTryptophan (5-BrW) is an analog of the tryptophan (Trp) effector and inhibits the gelation of hemoglobin S. |
| Synonyms | L-5-溴色氨酸, 5-BrW, 5 BrW |
| molecular weight | 283.12 |
| Molecular formula | C11H11BrN2O2 |
| CAS | 25197-99-3 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 27.5 mg/ml (97.13 mM) |
| References | 1. Kwon I, Tirrell DA. Site-specific incorporation of tryptophan analogues into recombinant proteins in bacterial cells. J Am Chem Soc. 2007 Aug 29;129(34):10431-7. Epub 2007 Aug 8 2. De Croos PZ, et al. Hemoglobin S antigelation agents based on 5-bromotryptophan with potential for sickle cell anemia. J Med Chem. 1990 Dec;33(12):3138-42. |