| Description | KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer. |
| molecular weight | 313.42 |
| Molecular formula | C17H19N3OS |
| CAS | 1029721-36-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Cho YH, Cha PH, Kaduwal S, Park JC, Lee SK, Yoon JS, Shin W, Kim H, Ro EJ, Koo KH, Park KS, Han G, Choi KY. KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer. Oncotarget. 2016 Dec 6;7(49):81727-81740. doi: 10.18632/oncotarget.13172. PubMed PMID: 27835580; PubMed Central PMCID: PMC5348425. |