| Description | KRAS inhibitor-15 (compound 3-19) is a potent inhibitor of KRAS G12C (IC50: 0.954 μM). KRAS inhibitor-15 exhibits p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 2.03, >33.3 μM, respectively. KRAS inhibitor-15 has potential to be studied in pancreatic, colorectal and lung cancers. |
| molecular weight | 451.34 |
| Molecular formula | C20H17Cl2FN4OS |
| CAS | 2230873-75-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |