| Description | 1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of inflammatory and neuropathic pain, the mechanism may be associated with the upregulation of allopregnanolone in the spinal cord. |
| molecular weight | 306.4 |
| Molecular formula | C20H22N2O |
| CAS | 1358-76-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble DMSO: 14 mg/mL (45.7 mM) |
| References | 1. Zhang X , Chen Y , Gao B , et al. Apoptotic Effect of Koumine on Human Breast Cancer Cells and the Mechanism Involved[J]. Cell Biochemistry & Biophysics, 2015, 72(2):411-416. |