| Description | KN-92 is an inactive analog of the CaM kinase II inhibitor KN 93. |
| Synonyms | K92, KN-92 free base, K 92 |
| molecular weight | 456.98 |
| Molecular formula | C24H25ClN2O3S |
| CAS | 176708-42-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: Soluble |
| References | 1. Takeuchi M, Yamamoto T. Apoptosis induced by NAD depletion is inhibited by KN-93 in a CaMKII-independent manner. Exp Cell Res. 2015 Jul 1;335(1):62-7. doi: 10.1016/j.yexcr.2015.05.019. PubMed PMID: 26024774. 2. Ke J, Chen F, Zhang C, Xiao X, Tu J, Dai M, Wang X, Chen B, Chen M. Effects of calmodulin-dependent protein kinase II inhibitor, KN-93, on electrophysiological features of rabbit hypertrophic cardiac myocytes. J Huazhong Univ Sci Technolog Med Sci. 2012 Aug;32(4):485-9. doi: 10.1007/s11596-012-0084-9. PubMed PMID: 22886958. 3. Popovic MA, Stojilkovic SS, Gonzalez-Iglesias AE. Effects of isoquinolonesulfonamides on action potential secretion coupling in pituitary cells. Horm Mol Biol Clin Investig. 2010 Jan;1(1):35-42. doi: 10.1515/HMBCI.2010.005. PubMed PMID: 25961970. 4. An P, Zhu JY, Yang Y, Lv P, Tian YH, Chen MK, Luo HS. KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro. World J Gastroenterol. 2007 Mar 7;13(9):1445-8. PubMed PMID: 17457979; PubMed Central PMCID: PMC4146932. |