| Description | Keto-pantoyllactone (Dihydro-4,4-dimethyl-2,3-furandione) is assayed by the ketopantoyl lactone-dependent oxidation of nicotinamide adenine dinucleotide phosphate. |
| Synonyms | 二氢-4,4-二甲基-2,3-呋喃二酮, Keto pantoyllactone, Ketopantoyllactone, Dihydro-4,4-dimethyl-2,3-furandione |
| molecular weight | 128.13 |
| Molecular formula | C6H8O3 |
| CAS | 13031-04-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 4.8 mg/mL (37.46 mM) |
| References | 1. King HL Jr, Dyar RE, Wilken DR. Ketopantoyl lactone and ketopantoic acid reductases. Characterization of the reactions and purification of two forms of ketopantoyl lactone reductase. J Biol Chem. 1974 Aug 10;249(15):4689-95. 2. Hata H, et al. Ketopantoyl lactone reductase is a conjugated polyketone reductase. FEMS Microbiol Lett. 1989 Mar;49(1):87-90. 3. Qin HM, et al. Structure of conjugated polyketone reductase from Candida parapsilosis IFO 0708 reveals conformational changes for substrate recognition upon NADPH binding. Appl Microbiol Biotechnol. 2014 Jan;98(1):243-9. 4. Lanzilotta RP, Bradley DG, McDonald KM. Microbial reduction of ketopantoyl lactone to pantoyl lactone. Appl Microbiol. 1974 Jan;27(1):130-4. |