| Description | JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD). |
| Synonyms | JTZ-951, JTZ 951 hydrochloride, JTZ951 HCl, JTZ 951 |
| molecular weight | 376.79 |
| Molecular formula | C17H17ClN4O4 |
| CAS | 1262131-60-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Discovery of JTZ-951: A HIF Prolyl Hydroxylase Inhibitor for the Treatment of Renal Anemia Yosuke Ogoshi, Takuya Matsui, Ikuo Mitani, Masahiro Yokota, Masakazu Terashita, Dai Motoda, Kazuhito Ueyama, Takahiro Hotta, Takashi Ito, Yasunori Hase, Kenji Fukui, Katsuya Deai, Hiromi Yoshiuchi, Soichiro Ito, and Hiroyuki Abe Publication Date (Web): November 20, 2017 (Letter) doi: 10.1021/acsmedchemlett.7b00404 |