| Description | JTC-017 is an antagonist of Corticotropin-releasing hormone receptor 1. |
| Synonyms | JTC 017 |
| molecular weight | 490.4 |
| Molecular formula | C20H25Cl2N3O5S |
| CAS | 357330-77-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Saito K, Kasai T, Nagura Y, Ito H, Kanazawa M, Fukudo S. Corticotropin-releasing hormone receptor 1 antagonist blocks brain-gut activation induced by colonic distention in rats. Gastroenterology. 2005 Nov;129(5):1533-43. PubMed PMID: 16285953. 2. Uetsuki N, Segawa H, Mayahara T, Fukuda K. The role of CRF1 receptors for sympathetic nervous response to laparotomy in anesthetized rats. Brain Res. 2005 May 17;1044(1):107-15. Epub 2005 Apr 13. PubMed PMID: 15862795. |