| Description | JQ1-FITC, a fluorescent BET bromodomain probe, exhibits high affinity binding to BRD4(BD1) and BRD4(BD2), with KD,app values of 6.5 nM and 5.8 nM respectively, as determined using GST-tagged BRD4 proteins in a CoraFluorTR-FRET assay; for BRD4(BD1), the value is 58.7 nM in a fluorescence anisotropy assay. It has excitation and emission maxima (λ) of 495 nm and 525 nm. |
| molecular weight | 1106.58 |
| Molecular formula | C50H50ClN7O9S2.CF3CO2H |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |