| Description | JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator. |
| In vivo | 向HBV基因型D感染的嵌合鼠投给JNJ-632 (54)，导致HBV DNA病毒载量下降2.77 log。 |
| molecular weight | 378.42 |
| Molecular formula | C18H19FN2O4S |
| CAS | 1572510-42-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 125 mg/mL (330.32 mM), Sonication is recommended. |
| References | 1. Synthesis and Evaluation of N-Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV)[J]. Journal of Medicinal Chemistry, 2018. |
| Citations | 1. Yin J, Feng Z, Li Z, et al.Synthesis and evaluation of N-sulfonylpiperidine-3-carboxamide derivatives as capsid assembly modulators inhibiting HBV in vitro and in HBV-transgenic mice.European Journal of Medicinal Chemistry.2023: 115141. |