| Description | JHU-58 is a novel dipeptide MrgC agonist. JHU-58 inhibited both mechanical and heat hypersensitivity in rats after an L5 spinal nerve ligation (SNL). JHU58 attenuated the evoked excitatory postsynaptic currents in substantia gelatinosa (SG) neurons in wild-type mice, but not in Mrg knockout mice, after peripheral nerve injury. |
| molecular weight | 368.43 |
| Molecular formula | C19H24N6O2 |
| CAS | 1632140-61-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |