| Description | JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis. Additionally, it attenuates primary tumor growth and metastases, augmenting the efficacy of checkpoint inhibitors [1]. |
| molecular weight | 481.56 |
| Molecular formula | C29H28FN5O |
| CAS | 2308504-22-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |