| Description | JAK-IN-23 is an orally active dual JAK/STAT and NF-κB inhibitor that inhibits J AK1 (IC50: 8.9 nM), J AK2 (IC50: 15 nM), and J AK3 (IC50: 46.2 nM). JAK-IN-23 exhibits strong anti-inflammatory effects and can reduce the release of various pro-inflammatory factors.JAK-IN-23 can be used to study inflammatory bowel disease (IBD). |
| molecular weight | 441.35 |
| Molecular formula | C23H22Cl2N4O |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |