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(±)-J 113397

CAS No.: 217461-40-0

(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM). J-113397
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Description (±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM). J-113397 inhibited nociceptin/orphanin FQ-stimulated GTPγS binding to CHO cells expressing ORL1 with an IC 50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ [1].
molecular weight 399.57
Molecular formula C24H37N3O2
CAS 217461-40-0
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year