| Description | ISX-3 is a potent pro-osteogenic and anti-adipogenic agent. ISX-3 can increase the expression of PPARγ. ISX-3 can be for the research of osteopenia and osteoporosis. |
| In vitro | ISX-3（0-100000 nM；10天）在脂滴积累上展现出促进作用，在ALP诱导上显示出抑制效果。ISX-3（50 µM；2天）在MDI[1]存在的情况下，提高了hBMSCs中PPARγ的表达。 |
| molecular weight | 330.77 |
| Molecular formula | C16H15ClN4O2 |
| CAS | 912789-08-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 11 mg/mL (33.26 mM) |
| References | 1. Nawa K, et al. Discovering small molecules that inhibit adipogenesis and promote osteoblastogenesis: unique screening and Oncostatin M-like activity. Differentiation. 2013 Jul-Sep;86(1-2):65-74. |