| Description | Isobutylshikonin exhibits obvious antioxidant activities , it exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·. |
| In vitro | 从韩国栽培的紫草（Lithospermum erythrorhizon）根中分离出五种赤色Shikonin类色素，包括脱氧Shikonin、Shikonin、乙酰基Shikonin、Isobutylshikonin和β-羟基异戊酰基Shikonin。纯化后的色素在酸性、中性和碱性pH值下分别呈现红色、紫色和蓝色。对这些纯化色素在水溶液中对热和光的物理稳定性进行了研究，以探寻其作为增值食品色素的可能性。热降解反应在pH 3.0 (50 mM 甘氨酸缓冲液)的条件下进行，并使用50% EtOH/H(2)O作为溶剂。脱氧Shikonin(t(1/2) = 14.6 h, 60摄氏度)和Isobutylshikonin(t(1/2) = 19.3 h, 60 摄氏度)的稳定性相对于其他Shikonin衍生物(t(1/2) = 40-50 h, 60 摄氏度)来说较低。计算了分离出的色素的热降解活化能。脱氧Shikonin的活化能最高（12.5 kcal mol(-)(1)），而β-羟基异戊酰基Shikonin的活化能最低（1.71 kcal mol(-)(1)）。 |
| molecular weight | 358.39 |
| Molecular formula | C20H22O6 |
| CAS | 52438-12-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: Slightly soluble |
| References | 1. Cho MH, Paik YS, Hahn TR. Physical stability of shikonin derivatives from the roots of Lithospermum erythrorhizon cultivated in Korea. J Agric Food Chem. 1999 Oct;47(10):4117-20. 2. H Damianakos, et al. Shikonin pigments from hairy root culture of Lithospermum canescens. Planta Med 2007; 73 - P_185. |