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Isobavachromene

CAS No.: 52801-22-6

Isobavachromene is an inhibitor of NADH-Ubiquinone oxidoreductase and ornithine decarboxylase. Isobavachromene has antif
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Description Isobavachromene is an inhibitor of NADH-Ubiquinone oxidoreductase and ornithine decarboxylase. Isobavachromene has antifungal activity.
In vitro 巴豆醇、补骨脂素、异鲍鱼脂素、Isobavachromene 及巴豆苦素为乙醇提取物中的主要成分。通过各种体外实验研究了补骨脂(Psoralea corylifolia L.)乙醇提取物及其活性成分的雌激素活性。在分馏过程中,正己烷和氯仿部分在酵母转录激活实验和E-screen实验中显示出雌激素活性。在酵母转录激活实验中,乙醇提取物、正己烷和氯仿部分在1.0 ng/ml的浓度下显示出明显较高的活性;特别是,巴豆醇在10(-6) M浓度时显示出的活性最高,其活性甚至超过了相同浓度下的槲皮素[1]。
molecular weight 322.35
Molecular formula C20H18O4
CAS 52801-22-6
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 25 mg/mL (77.56 mM)
References 1. Estrogenic activities of Psoralea corylifolia L. seed extracts and main constituents.Phytomedicine. 2011 Mar 15;18(5):425-30.