| Description | Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia. |
| Cell experiments | in vitro experiments on human peritoneal, the mesothelial effect of elemental iron (in conc. 0.0001-1 mg mL-1) present in Venofer on their viability, growth and synthesis of IL-6 was studied. Additionally we evaluated with a fluorescent probe (2',7'-dichlorodihydro-fluorescein diacatate) generation of reactive oxygen species in cells exposed to iron sucrose. We also measured accumulation of iron in the cytoplasm of mesothelial cells after their in vitro exposure to Venofer[1]. |
| Synonyms | Iron saccharate, 蔗糖铁, Sucroferric oxyhydroxide |
| molecular weight | 736.1 |
| Molecular formula | C18H24Fe2O24 |
| CAS | 8047-67-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (81.51 mM) H2O: 100 mg/mL (135.85 mM) |
| References | 1. Breborowicz M , Polubinska A , Tam P , et al. Effect of iron sucrose on human peritoneal mesothelial cells[J]. European Journal of Clinical Investigation, 2003, 33(12):1038-1044. 2. Kaneva K , Chow E , Rosenfield C G , et al. Intravenous Iron Sucrose for Children With Iron Deficiency Anemia[J]. Journal of Pediatric Hematology/oncology, 2017:1. |