| Description | Ipomoeassin F, a selective and potent inhibitor of endoplasmic reticulum (ER) protein translocation, targets the Sec61 complex's pore-forming subunit (Sec61α) at the ER membrane. It inhibits the ER membrane translocation of SARS-CoV-2 proteins and blocks the ER translocation of secretory and type I transmembrane proteins (TMPs), without affecting type III TMPs [1] [2] [3]. |
| molecular weight | 830.95 |
| Molecular formula | C44H62O15 |
| CAS | 915392-44-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |