| Description | Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan. |
| In vitro | Inulin(20 g/d及40 g/d)显著增加粪便中双歧杆菌的数量。[1] Inulin对健康促进菌属双歧杆菌的增殖具有优先刺激作用，同时使潜在致病菌（大肠杆菌、梭状芽孢杆菌）的数量保持在相对较低的水平。[2] Inulin与双歧杆菌的结合比单独使用二者更能有效抑制异型隐窝灶(ACF)，实现小型ACF 80%的抑制效果。[3] Inulin由线性果糖分子链组成，聚合度(DP)在3至65之间，可分为缓慢发酵的长链部分（DP范围从10到65，平均25）或快速发酵的低聚果糖部分（DP范围从3到8，平均4）。[4] 长链Inulin与短链低聚果糖的结合在大鼠中比对照组产生更多的盲肠、结肠和粪便中的Clostridium coccoides-Eubacterium rectale菌群，而单独的OF对这一菌群在盲肠、结肠或粪便中没有影响。[5] |
| In vivo | Inulin 在给予含有 Inulin 饮食的大鼠中导致盲肠重量增加和 beta-glucosidase 活性增加, 同时盲肠 pH 值降低（无论是否含有 B. longum）。[3] |
| Synonyms | 菊糖 |
| molecular weight | N/A |
| Molecular formula | C6nH10n+2O5n+1 |
| CAS | 9005-80-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | Ethanol: < 1 mg/mL (insoluble or slightly soluble) H2O: 95 mg/mL DMSO: 50 mg/mL (101.96 mM) |
| References | 1. Roberfroid MB, et al. J Nutr, 1998, 128(1), 11-19. 2. Wang X, et al. J Appl Bacteriol, 1993, 75(4), 373-380. 3. Rowland IR, et al. Carcinogenesis, 1998, 19(2), 281-285. 4. Femia AP, et al. Carcinogenesis, 2002, 23(11), 1953-1960. 5. Kleessen B, et al. Br J Nutr, 2001, 86(2), 291-300. 6. Shoaib M, et al. Inulin: Properties, health benefits and food applications. Carbohydr Polym. 2016 Aug 20;147:444-454. |