| Description | Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and possesses antiandrogenic activity in animal models. |
| Synonyms | RU-38882, RU 38882, RU38882, RU-882, RU 882 |
| molecular weight | 290.4 |
| Molecular formula | C18H26O3 |
| CAS | 83646-86-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lookingbill DP, Abrams BB, Ellis CN, Jegasothy BV, Lucky AW, Ortiz-Ferrer LC, Savin RC, Shupack JL, Stiller MJ, Zone JJ, et al. Inocoterone and acne. The effect of a topical antiandrogen: results of a multicenter clinical trial. Arch Dermatol. 1992 Sep;128(9):1197-200. PubMed PMID: 1387778. 2. Bouton MM, Lecaque D, Secchi J, Tournemine C. Effect of a new topically active antiandrogen (RU 38882) on the rat sebaceous gland: comparison with cyproterone acetate. J Invest Dermatol. 1986 Feb;86(2):163-7. PubMed PMID: 2943819. 3. Matias JR, Gaillard M. Local inhibition of sebaceous gland growth by topically applied RU 58841. Ann N Y Acad Sci. 1995 Jun 12;761:56-65. PubMed PMID: 7625751. 4. Cunliffe WJ, Bottomley WW. Antiandrogens and acne. A topical approach? Arch Dermatol. 1992 Sep;128(9):1261-4. PubMed PMID: 1387779. |