| Description | 1. Ingenol ((-)-Ingenol) mebutate is an effective treatment for actinic keratosis. 2. Formulating novel derivatives from Ingenol esters may be an innovative approach to develop new lead compounds to reactivate latent HIV. 3. Ingenol is a weak PKC activator and possesses important anticancer activity. |
| Target activity | PKC:30 μM(Ki) |
| Synonyms | (-)-Ingenol, 巨大戟二萜醇, 巨大戟醇 |
| molecular weight | 348.43 |
| Molecular formula | C20H28O5 |
| CAS | 30220-46-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (143.5 mM) |
| References | 1. Batalla A , Flórez, á, Feal C , et al. Clinical Response to Ingenol Mebutate in Patients With Actinic Keratoses[J]. Actas Dermo-Sifiliográficas (English Edition), 2015, 106(10):e55-e61. |