| Description | Indecainide (Ricainid) is a novel antiarrhythmic compound that is carcinogenic and can be used to study chronic stable ventricular arrhythmias secondary to coronary artery disease or cardiomyopathy. |
| In vivo | Indecainide(1-5 mg/kg;静脉注射)能够降低狗的心脏收缩能力[1]。 |
| Synonyms | Ricainide, Ricainid, Decabid, Indecainidum, Indecainida |
| molecular weight | 308.42 |
| Molecular formula | C20H24N2O |
| CAS | 74517-78-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. D R Holland, et al. Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14(3):454-61. 2. Lindstrom T D, et al. Metabolism of the antiarrhythmic agent, indecainide, in rats, dogs, and monkeys. Drug metabolism and disposition, 1984, 12(6): 691-697. 3. Dennis PD, Vaughan Williams EM. Effects on rabbit cardiac potentials of aprindine and indecainide, a new antiarrhythmic agent, in normoxia and hypoxia. Br J Pharmacol. 1985 May;85(1):11-9. 4. Sandusky GE Jr, Meyers DB. Toxicology of indecainide hydrochloride in mice, rats, and dogs. Fundam Appl Toxicol. 1985 Feb;5(1):175-81. |