| Description | Imupedone (LF 1695) is a synthetic immunomodulator that modulates T lymphocytes and macrophages, induces T-cell differentiation of bone marrow precursor cells, and increases the proliferative response of lymphocytes to mitogens, antigens, and allogeneic cells. |
| Synonyms | LF1695, LF-1695, LF 1695 |
| molecular weight | 328.84 |
| Molecular formula | C19H21ClN2O |
| CAS | 86187-86-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Touraine JL. Effect of the immunomodulator LF 1695 on T-lymphocytes and macrophages. Activity in HIV infection. Med Oncol Tumor Pharmacother. 1989;6(1):59-61. 2. Thorel T,et al. In vitro and in vivo immunomodulation by LF 1695 of human and rat macrophages and platelets in schistosomiasis. Int J Immunopharmacol. 1988;10(6):739-46. 3. Hullin F,et al. Stimulation of 12-HETE production in human platelets by an immunomodulator, LF 1695. Evidence for activation of arachidonate liberation coupled to cyclo-oxygenase inhibition. Biochem Pharmacol. 1989 Sep 1;38(17):2763-72. 4. Pascal M,et al. Increased interleukin-1 and modulation of interleukin-2 production by murine macrophages and lymphocytes treated with LF 1695. Int J Immunopharmacol. 1986;8(5):499-508. |